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Peptide record

TPDB22762

Antibacterial Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB22762
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 22-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
LGVPVSSTLRLNNTTMNPCLPS
Physicochemical Analysis
C98H168N28O32S2
ADEQHIKFWY
L
2314.70
9.01
1
0
7
+1
1.67
0.150
97.27
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
10
Residue Composition
number
0
A
1
R
3
N
0
D
1
C
0
E
0
Q
1
G
0
H
0
I
4
L
0
K
1
M
0
F
3
P
3
S
3
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 1 N: 3 D: 0 C: 1 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 4 K: 0 M: 1 F: 0 P: 3 S: 3 T: 3 W: 0 Y: 0 V: 2
Chemical Descriptors
22
C98H168N28O32S2
2314.70
9.01
+1
1.67
0.150
Evidence Records 7 records
Evidence 1 Activity

Activity

MIC
Antibacterial
37.7 µM

Target

C. fangi

Source & Reference

NA

Other

active against C. fangi (MIC 37.7 uM), C. michiganensis (MIC 34.6 uM), X. oryzae pv. oryzae (MIC 44.0 uM), R. solanacearum (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
34.6 µM

Target

C. michiganensis

Source & Reference

NA

Other

active against C. fangi (MIC 37.7 uM), C. michiganensis (MIC 34.6 uM), X. oryzae pv. oryzae (MIC 44.0 uM), R. solanacearum (MIC 33 uM), X. oryzae pv. oryzicola
Evidence 3 Activity

Activity

MIC
Antibacterial
44.0 µM

Target

v. oryzae

Source & Reference

NA

Other

active against C. fangi (MIC 37.7 uM), C. michiganensis (MIC 34.6 uM), X. oryzae pv. oryzae (MIC 44.0 uM), R. solanacearum (MIC 33 uM), X. oryzae pv. oryzicola (MIC 31.4 uM), and B. subtilis 168
Evidence 4 Activity

Activity

MIC
Antibacterial
33 µM

Target

R. solanacearum

Source & Reference

NA

Other

fangi (MIC 37.7 uM), C. michiganensis (MIC 34.6 uM), X. oryzae pv. oryzae (MIC 44.0 uM), R. solanacearum (MIC 33 uM), X. oryzae pv. oryzicola (MIC 31.4 uM), and B. subtilis 168 (MIC 36.1 uM).
Evidence 5 Activity

Activity

MIC
Antibacterial
31.4 µM

Target

v. oryzicola

Source & Reference

NA

Other

MIC 34.6 uM), X. oryzae pv. oryzae (MIC 44.0 uM), R. solanacearum (MIC 33 uM), X. oryzae pv. oryzicola (MIC 31.4 uM), and B. subtilis 168 (MIC 36.1 uM).
Evidence 6 Activity

Activity

MIC
Antibacterial
36.1 µM

Target

B. subtilis 168

Source & Reference

NA

Other

ae (MIC 44.0 uM), R. solanacearum (MIC 33 uM), X. oryzae pv. oryzicola (MIC 31.4 uM), and B. subtilis 168 (MIC 36.1 uM).
Evidence 7 Activity

Activity

0.306% Hemolysis
Toxicity
132 µM
Hemolytic Cytotoxic
0.306% Hemolysis | 132 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Isolation of Antimicrobial Genes from Oryza rufipogon Griff by Using a Bacillus subtilis Expression System with Potential Antimicrobial Activities. | Int J Mol Sci | 2020