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Peptide record

TPDB22743

Antibacterial Antifungal standard
98 amino acids
Basic Information
3D PDB MODEL
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TPDB22743
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 98-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
LGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGAWAAEVISNARENIQRLTGHGAEDSLADQAANKWGRSGRDPNHFRPAGLPEKY
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C471H707N149O146S2
C
A
10856.83
7.81
17
14
37
+0
2.73
-1.004
47.14
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
23950
2.21
19
Residue Composition
number
16
A
10
R
6
N
8
D
0
C
6
E
2
Q
12
G
3
H
3
I
4
L
4
K
2
M
3
F
4
P
5
S
1
T
3
W
5
Y
1
V
Amino Acid Distribution
A: 16 R: 10 N: 6 D: 8 C: 0 E: 6 Q: 2 G: 12 H: 3 I: 3 L: 4 K: 4 M: 2 F: 3 P: 4 S: 5 T: 1 W: 3 Y: 5 V: 1
Chemical Descriptors
98 reviewed residue count
C471H707N149O146S2 sequence-only estimate (linear, free termini)
10856.83 sequence-only estimate (linear, free termini)
7.81 sequence-only estimate (linear, free termini)
+0 sequence-only estimate (linear, free termini)
2.73 sequence-only estimate (linear, free termini)
-1.004 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Active against E. coli and S. aureus at acidic pH 5.5. You can rotate, zoom, and view the 3D structure here in the PDB .
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

Active against E. coli and S. aureus at acidic pH 5.5. You can rotate, zoom, and view the 3D structure here in the PDB .