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Peptide record

TPDB22729

Antibacterial Antiviral Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB22729
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
LEHGSCVTTMAKDKPTL
Physicochemical Analysis
C77H131N21O26S2
RNQIFWY
T
1831.13
7.16
3
2
5
+0
5.51
-0.288
68.82
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
5
Residue Composition
number
1
A
0
R
0
N
1
D
1
C
1
E
0
Q
1
G
1
H
0
I
2
L
2
K
1
M
0
F
1
P
1
S
3
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 1 E: 1 Q: 0 G: 1 H: 1 I: 0 L: 2 K: 2 M: 1 F: 0 P: 1 S: 1 T: 3 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C77H131N21O26S2
1831.13
7.16
+0
5.51
-0.288
Evidence Records 3 records
Evidence 1 Activity

Activity

<10% Cell death
Toxicity
50 µM
Cytotoxic
<10% Cell death | 50 | µM | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
In vitro analysis of synthetic peptides in blocking the entry of dengue virus. | Virus Res | 2019
Evidence 2 Activity

Activity

20% Cell death
Toxicity
200 µM
Cytotoxic
20% Cell death | 200 | µM | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
In vitro analysis of synthetic peptides in blocking the entry of dengue virus. | Virus Res | 2019
Evidence 3 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.30508603]<20% cytotoxicity against Vero and C6/36 cells at 200 µM.

Source & Reference

NA
DRAMP
Virus Res. 2019 Jan 15 260:142-150.