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Peptide record

TPDB22692

Antibacterial Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB22692
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
LARLRRLCFLWAAAWPWPWR
Physicochemical Analysis
C126H182N36O21S1
NDEQGHIKMSTYV
ARLW
2569.12
12.40
4
0
13
+4
-7.55
0.145
98.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
22000
856.32
1
Residue Composition
number
4
A
4
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
4
L
0
K
0
M
1
F
2
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 4 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 0 M: 0 F: 1 P: 2 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
20
C126H182N36O21S1
2569.12
12.40
+4
-7.55
0.145
Evidence Records 11 records
Evidence 1 Activity

Activity

MIC
Antibacterial
8 µM

Target

p. michiganensis

Source & Reference

NA

Other

Active against C. michiganensis subsp. michiganensis (MIC 8 uM), C. fangii (MIC 8 uM), B. subtilis 168 (MIC 16 uM), R. solanacearum (MIC 8 uM), P. syring
Evidence 2 Activity

Activity

MIC
Antibacterial
8 µM

Target

C. fangii

Source & Reference

NA

Other

Active against C. michiganensis subsp. michiganensis (MIC 8 uM), C. fangii (MIC 8 uM), B. subtilis 168 (MIC 16 uM), R. solanacearum (MIC 8 uM), P. syringae pv. tomato DC3000 (
Evidence 3 Activity

Activity

MIC
Antibacterial
16 µM

Target

B. subtilis 168

Source & Reference

NA

Other

Active against C. michiganensis subsp. michiganensis (MIC 8 uM), C. fangii (MIC 8 uM), B. subtilis 168 (MIC 16 uM), R. solanacearum (MIC 8 uM), P. syringae pv. tomato DC3000 (MIC 4 uM), P. syringae pv. sy
Evidence 4 Activity

Activity

MIC
Antibacterial
8 µM

Target

R. solanacearum

Source & Reference

NA

Other

ensis subsp. michiganensis (MIC 8 uM), C. fangii (MIC 8 uM), B. subtilis 168 (MIC 16 uM), R. solanacearum (MIC 8 uM), P. syringae pv. tomato DC3000 (MIC 4 uM), P. syringae pv. syringae (MIC 4 uM), X. oryzae
Evidence 5 Activity

Activity

MIC
Antibacterial
4 µM

Target

v. tomato DC3000

Source & Reference

NA

Other

fangii (MIC 8 uM), B. subtilis 168 (MIC 16 uM), R. solanacearum (MIC 8 uM), P. syringae pv. tomato DC3000 (MIC 4 uM), P. syringae pv. syringae (MIC 4 uM), X. oryzae pv. oryzae (MIC 4 uM), X. campestris pv.
Evidence 6 Activity

Activity

MIC
Antibacterial
4 µM

Target

v. syringae

Source & Reference

NA

Other

6 uM), R. solanacearum (MIC 8 uM), P. syringae pv. tomato DC3000 (MIC 4 uM), P. syringae pv. syringae (MIC 4 uM), X. oryzae pv. oryzae (MIC 4 uM), X. campestris pv. holcicola (MIC 4 uM), Dickeya zeae (M
Evidence 7 Activity

Activity

MIC
Antibacterial
4 µM

Target

v. oryzae

Source & Reference

NA

Other

P. syringae pv. tomato DC3000 (MIC 4 uM), P. syringae pv. syringae (MIC 4 uM), X. oryzae pv. oryzae (MIC 4 uM), X. campestris pv. holcicola (MIC 4 uM), Dickeya zeae (MIC 16 uM), P. carotovorum subsp.
Evidence 8 Activity

Activity

MIC
Antibacterial
4 µM

Target

v. holcicola

Source & Reference

NA

Other

uM), P. syringae pv. syringae (MIC 4 uM), X. oryzae pv. oryzae (MIC 4 uM), X. campestris pv. holcicola (MIC 4 uM), Dickeya zeae (MIC 16 uM), P. carotovorum subsp. carotovorum (MIC 16 uM), Erwinia amylovo
Evidence 9 Activity

Activity

MIC
Antibacterial
16 µM

Target

p. carotovorum

Source & Reference

NA

Other

uM), X. campestris pv. holcicola (MIC 4 uM), Dickeya zeae (MIC 16 uM), P. carotovorum subsp. carotovorum (MIC 16 uM), Erwinia amylovora (MIC 8 uM), Agrobacterium vitis (MIC 8 uM), E. coli DH5alpha or DE3 (M
Evidence 10 Activity

Activity

MIC
Antibacterial
16 µM

Target

Escherichia coli DH5alpha or DE3

Source & Reference

NA

Other

p. carotovorum (MIC 16 uM), Erwinia amylovora (MIC 8 uM), Agrobacterium vitis (MIC 8 uM), E. coli DH5alpha or DE3 (MIC 16 uM).
Evidence 11 Activity

Activity

10% Hemolysis
Toxicity
512 µM
Hemolytic Cytotoxic
10% Hemolysis | 512 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Prediction and Activity of a Cationic α-Helix Antimicrobial Peptide ZM-804 from Maize. | Int J Mol Sci | 2021