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Peptide record

TPDB22681

Antibacterial Toxicity modified_plain modified
12 amino acids
Basic Information
3D PDB MODEL
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TPDB22681
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 12-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
KXXKRRVRWIIW
Physicochemical Analysis
C69H113N23O11
ANDCEQGHLMFPSTY
R
1440.80
12.71
5
0
5
+5
0.16
-0.825
89.17
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
11000
763.46
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
0
L
2
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 1
Chemical Descriptors
12
C69H113N23O11
1440.80
12.71
+5
0.16
-0.825
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>250 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >250 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The effect of lipidation and glycosylation on short cationic antimicrobial peptides. | Biochim Biophys Acta | 2020