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Peptide record

TPDB22673

Antibacterial Toxicity modified_plain modified
15 amino acids
Basic Information
3D PDB MODEL
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TPDB22673
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 15-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
KXWKLXKXKXWKLXK
Physicochemical Analysis
C70H116N18O11
ARNDCEQGHIMFPSTYV
K
1385.81
11.21
6
0
4
+6
1.12
-1.173
52.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
11000
793.76
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
2
L
6
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
15
C70H116N18O11
1385.81
11.21
+6
1.12
-1.173
Evidence Records 4 records
Evidence 1 Activity

Activity

24.9% Hemolysis
Toxicity
12.5 µM
Hemolytic Cytotoxic
24.9% Hemolysis | 12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial and Hemolytic Activity of Stapled Heptapeptide Dimers | Bull Korean Chem Soc | 2016
Evidence 2 Activity

Activity

14.2% Hemolysis
Toxicity
6.3 µM
Hemolytic Cytotoxic
14.2% Hemolysis | 6.3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial and Hemolytic Activity of Stapled Heptapeptide Dimers | Bull Korean Chem Soc | 2016
Evidence 3 Activity

Activity

24.4% Hemolysis
Toxicity
12.5 µM
Hemolytic Cytotoxic
24.4% Hemolysis | 12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial and Hemolytic Activity of Stapled Heptapeptide Dimers | Bull Korean Chem Soc | 2016
Evidence 4 Activity

Activity

12.9% Hemolysis
Toxicity
6.3 µM
Hemolytic Cytotoxic
12.9% Hemolysis | 6.3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial and Hemolytic Activity of Stapled Heptapeptide Dimers | Bull Korean Chem Soc | 2016