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Peptide record

TPDB22668

Antibacterial Toxicity modified_plain modified
7 amino acids
Basic Information
3D PDB MODEL
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TPDB22668
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 7-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
KXWKFXK
Physicochemical Analysis
C38H57N9O6
ARNDCEQGHILMPSTYV
K
735.93
10.84
3
0
2
+3
-0.01
-1.400
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
747.36
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
3
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 3 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
7
C38H57N9O6
735.93
10.84
+3
-0.01
-1.400
Evidence Records 2 records
Evidence 1 Activity

Activity

4.4% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
4.4% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Mono-substitution effects on antimicrobial activity of stapled heptapeptides. | Arch Pharm Res | 2017
Evidence 2 Activity

Activity

1.9% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
1.9% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Mono-substitution effects on antimicrobial activity of stapled heptapeptides. | Arch Pharm Res | 2017