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Peptide record

TPDB22641

Antibacterial Anticancer Toxicity modified_plain modified
17 amino acids
Basic Information
3D PDB MODEL
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TPDB22641
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 17-aa modified multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
LCXIIKKIIKKIIKKII
Physicochemical Analysis
C93H178N22O17S1
ARNDEQGHMFPSTWYV
I
1908.63
10.82
6
0
9
+6
2.66
1.112
206.47
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
8
I
1
L
6
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 8 L: 1 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
17
C93H178N22O17S1
1908.63
10.82
+6
2.66
1.112
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
Toxicity
81±8 µM
Cytotoxic
IC50 | 81±8 | µM | target cell: Human dermal fibroblasts

Target

Human dermal fibroblasts

Source & Reference

NA
DBAASP
Rationally designed short cationic α-helical peptides with selective anticancer activity. | J Colloid Interface Sci | 2022
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
J Colloid Interface Sci. 2022 Feb 607(Pt 1):488-501.