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Peptide record

TPDB22620

Antibacterial standard
70 amino acids
Basic Information
3D PDB MODEL
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TPDB22620
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 70-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
LAKEFGIPAAVAGTVLNVVEAGGWVTTIVSILTAVGSGGLSLLAAAGRESIKAYLKKEIKKKGKRAVIAW
Physicochemical Analysis
C329H551N87O89
DCQHM
A
7149.52
10.57
10
4
37
+6
6.63
0.566
122.71
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
12490
174.70
10
Residue Composition
number
12
A
2
R
1
N
0
D
0
C
4
E
0
Q
9
G
0
H
6
I
7
L
8
K
0
M
1
F
1
P
4
S
4
T
2
W
1
Y
8
V
Amino Acid Distribution
A: 12 R: 2 N: 1 D: 0 C: 0 E: 4 Q: 0 G: 9 H: 0 I: 6 L: 7 K: 8 M: 0 F: 1 P: 1 S: 4 T: 4 W: 2 Y: 1 V: 8
Chemical Descriptors
70
C329H551N87O89
7149.52
10.57
+6
6.63
0.566
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12 µg/mL

Target

Escherichia coli DH5alpha

Source & Reference

NA

Other

Active against B. cereus ATCC14579, B. pumilus B4107, E. coli DH5alpha (MIC 12 ug/ml), M. flavus B423 (MIC 3 ug/ml), and S. pneumoniae D39 (MIC 47 ug/ml). Reg. 12/2021
Evidence 2 Activity

Activity

MIC
Antibacterial
3 µg/mL

Target

M. flavus B423

Source & Reference

NA

Other

Active against B. cereus ATCC14579, B. pumilus B4107, E. coli DH5alpha (MIC 12 ug/ml), M. flavus B423 (MIC 3 ug/ml), and S. pneumoniae D39 (MIC 47 ug/ml). Reg. 12/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
47 µg/mL

Target

S. pneumoniae D39

Source & Reference

NA

Other

579, B. pumilus B4107, E. coli DH5alpha (MIC 12 ug/ml), M. flavus B423 (MIC 3 ug/ml), and S. pneumoniae D39 (MIC 47 ug/ml). Reg. 12/2021