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Peptide record

TPDB22606

Antibacterial Anticancer Antifungal Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB22606
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
KYYGNGVHCTKSGCSVNW
Physicochemical Analysis
C87H127N25O26S2
ARDEQILMFP
G
2003.24
8.98
3
0
5
+2
0.14
-0.644
32.22
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
8605
429.55
9
Residue Composition
number
0
A
0
R
2
N
0
D
2
C
0
E
0
Q
3
G
1
H
0
I
0
L
2
K
0
M
0
F
0
P
2
S
1
T
1
W
2
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 0 C: 2 E: 0 Q: 0 G: 3 H: 1 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 2 T: 1 W: 1 Y: 2 V: 2
Chemical Descriptors
18
C87H127N25O26S2
2003.24
8.98
+2
0.14
-0.644
Evidence Records 1 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
>128 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | >128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Designed symmetrical β-hairpin peptides for treating multidrug-resistant salmonella typhimurium infections. | Eur J Med Chem | 2022