Peptide record

TPDB22554

Tpl Antibacterial Anticancer Cell-penetrating Peptides standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB22554
Tpl
Antibacterial Anticancer Cell-penetrating Peptides
Anti-infective peptides Cancer-related peptides Delivery and barrier-penetrating peptides
Peptipedia CellPPD-MOD CPPsite3.0 MLCPP 2.0 PerseuCPP
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, and Cell-penetrating Peptides) peptide sequence curated from Peptipedia, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
Sequence
KWCFRVCYRGICYRRCRGK
Physicochemical Analysis
C107H169N37O22S4
ANDEQHLMPST
R
2453.99
10.36
7
0
6
+7
-0.01
-0.689
35.79
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
8730
355.75
6
Residue Composition
number
0
A
5
R
0
N
0
D
4
C
0
E
0
Q
2
G
0
H
1
I
0
L
2
K
0
M
1
F
0
P
0
S
0
T
1
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 4 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 0 K: 2 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 2 V: 1
Chemical Descriptors
19
C107H169N37O22S4
2453.99
10.36
+7
-0.01
-0.689
Free
L
Cationic
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells , Triticum Aestivum Protoplasts, Root Tips, Coleoptiles And Hypocotyls

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L Cationic
Protein derived
β-glucuronidase enzyme
Nucleus
Successful delivery of β-galactosidase to the cells with an efficiency of > 90%
Direct membrane penetration
In vitro