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Peptide record

TPDB22528

Antibacterial Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB22528
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
KWLLKWLKKL
Physicochemical Analysis
C70H114N16O11
ARNDCEQGHIMFPSTYV
LK
1355.78
11.00
4
0
6
+4
-1.98
-0.220
156.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
11000
811.34
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
4
L
4
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
10
C70H114N16O11
1355.78
11.00
+4
-1.98
-0.220
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 32 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
10-mer and 9-mer WALK Peptides with Both Antibacterial and Anti-Inflammatory Activities. | Antibiotics (Basel) | 2022
Evidence 2 Activity

Activity

10% Cell death
Toxicity
8 µM
Cytotoxic
10% Cell death | 8 | µM | target cell: Murine macrophage cells J774A.1

Target

Murine macrophage cells J774A.1

Source & Reference

NA
DBAASP
10-mer and 9-mer WALK Peptides with Both Antibacterial and Anti-Inflammatory Activities. | Antibiotics (Basel) | 2022