Peptide record

TPDB22520

Antibacterial Anticancer Antifungal Toxicity standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB22520
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF CAFPdb DRAMP dbAMP
standard
No
A 6-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, AntiCP 2.0, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
KWKWKW
Physicochemical Analysis
C51H68N12O7
ARNDCEQGHILMFPSTYV
KW
961.18
10.84
3
0
3
+3
-2.58
-2.400
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
16500
1716.64
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
3
K
0
M
0
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
6
C51H68N12O7
961.18
10.84
+3
-2.58
-2.400
Evidence Records 2 records
Evidence 1 Activity

Activity

3% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
3% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A pilot study on ultrashort peptide with fluconazole: A promising novel anticandidal combination | Vet World | 2023
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
350 µM
Hemolytic Cytotoxic
10% Hemolysis | 350 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effect of repetitive lysine-tryptophan motifs on the bactericidal activity of antimicrobial peptides. | Amino Acids | 2013