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Peptide record

TPDB22511

Antibacterial Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB22511
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 26-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
KWKSFLKTFKSAKKTVLHTLKKAISS
Physicochemical Analysis
C142H237N37O34
RNDCEQGMPY
K
3006.67
11.36
9
0
10
+8
3.45
-0.435
78.85
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
182.93
7
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
1
I
3
L
8
K
0
M
2
F
0
P
4
S
3
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 3 K: 8 M: 0 F: 2 P: 0 S: 4 T: 3 W: 1 Y: 0 V: 1
Chemical Descriptors
26
C142H237N37O34
3006.67
11.36
+8
3.45
-0.435
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
<5% Hemolysis | 125 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-guided de novo design of alpha-helical antimicrobial peptide with enhanced specificity | Pure Appl Chem | 2010