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Peptide record

TPDB22508

Antibacterial Anticancer Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB22508
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
KWKSFLKTFKSAKKTVLHTAAKAISS
Physicochemical Analysis
C136H224N36O34
RNDCEQGMPY
K
2907.50
11.29
8
0
11
+7
2.68
-0.292
71.54
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
189.17
7
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
1
I
2
L
7
K
0
M
2
F
0
P
4
S
3
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 2 K: 7 M: 0 F: 2 P: 0 S: 4 T: 3 W: 1 Y: 0 V: 1
Chemical Descriptors
26
C136H224N36O34
2907.50
11.29
+7
2.68
-0.292
Evidence Records 3 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Studies on mechanism of action of anticancer peptides by modulation of hydrophobicity within a defined structural framework. | Mol Cancer Ther | 2011
Evidence 2 Activity

Activity

MHC
Toxicity
334.4 µm
Hemolytic Cytotoxic
Hemolytic_activity: Human red blood cells: MHC>334.4 µmol/L | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Mol Cancer Ther. 2011 Mar 10(3):416-26.
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Mol Cancer Ther. 2011 Mar 10(3):416-26.