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Peptide record

TPDB22487

Antibacterial Toxicity modified_plain modified
15 amino acids
Basic Information
3D PDB MODEL
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TPDB22487
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 15-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
KWKLFKKXGAVLKVL
Physicochemical Analysis
C83H140N20O15
RNDCEQHIMPSTY
K
1658.15
11.12
5
0
8
+5
0.27
0.240
123.33
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
331.70
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
3
L
5
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 3 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
15
C83H140N20O15
1658.15
11.12
+5
0.27
0.240
Evidence Records 1 records
Evidence 1 Activity

Activity

25% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
25% Hemolysis | 100 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Alpha,beta-dehydrophenylalanine containing cecropin-melittin hybrid peptides: conformation and activity. | J Pept Sci | 2007