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Peptide record

TPDB22482

Antibacterial Toxicity modified_plain modified
18 amino acids
Basic Information
3D PDB MODEL
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TPDB22482
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 18-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
KWKLFKKIXKFLHLAKKF
Physicochemical Analysis
C113H179N27O18
RNDCEQGMPSTYV
K
2203.83
11.29
8
0
9
+7
0.49
-0.294
92.22
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
249.57
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
1
I
3
L
7
K
0
M
3
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 3 K: 7 M: 0 F: 3 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
18
C113H179N27O18
2203.83
11.29
+7
0.49
-0.294
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
5% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial and anti-inflammatory activities of designed antimicrobial peptide P18 analogues. | Protein Pept Lett | 2008