Back to search

Peptide record

TPDB22480

Antibacterial Antiparasitic Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB22480
Antibacterial Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia dbAMP 3.0
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antiparasitic, and Toxicity) peptide sequence curated from Peptipedia and dbAMP 3.0, with an available 3D structural model.
Sequence
KWKLFKKILKVL
Physicochemical Analysis
C79H134N18O13
ARNDCEQGHMPSTY
K
1544.05
11.12
5
0
7
+5
0.05
0.208
154.17
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
356.21
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
3
L
5
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 3 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
12
C79H134N18O13
1544.05
11.12
+5
0.05
0.208
Evidence Records 1 records
Evidence 1 Activity

Activity

6% Hemolysis
Toxicity
2.5 µM
Hemolytic Cytotoxic
6% Hemolysis | 2.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of new leishmanicidal peptide lead structures by automated real-time monitoring of changes in intracellular ATP. | Biochem J | 2003