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Peptide record

TPDB22472

Antibacterial Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB22472
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 26-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
KWKSKLKTFKSLKKTVLHTLKKAISS
Physicochemical Analysis
C142H246N38O34
RNDCEQGMPY
K
3029.75
11.41
10
0
9
+9
5.18
-0.615
90.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
181.53
7
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
1
I
4
L
9
K
0
M
1
F
0
P
4
S
3
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 4 K: 9 M: 0 F: 1 P: 0 S: 4 T: 3 W: 1 Y: 0 V: 1
Chemical Descriptors
26
C142H246N38O34
3029.75
11.41
+9
5.18
-0.615
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
250 µg/mL
Hemolytic Cytotoxic
<5% Hemolysis | 250 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-guided de novo design of alpha-helical antimicrobial peptide with enhanced specificity | Pure Appl Chem | 2010