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Peptide record

TPDB22445

Antibacterial Antifungal Hemolysis Toxicity standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB22445
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP PD_Hemolysis
standard
No
A 3-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from Peptipedia, CAFPdb, dbAMP, and other sources, with an available 3D structural model.
Sequence
KWI
Physicochemical Analysis
C23H35N5O4
ARNDCEQGHLMFPSTYV
IKW
445.56
10.10
1
0
2
+1
-1.17
-0.100
130.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
1234.40
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
0
L
1
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
3
C23H35N5O4
445.56
10.10
+1
-1.17
-0.100
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
<<12.5 µM
Hemolytic Cytotoxic
50% Hemolysis | <<12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Small lipopeptides possess anti-biofilm capability comparable to daptomycin and vancomycin. | RSC Adv | 2015
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis