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Peptide record

TPDB22412

Antibacterial Hemolysis Toxicity standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB22412
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia PD_Hemolysis
standard
No
A 7-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from Peptipedia and PD_Hemolysis, with an available 3D structural model.
Sequence
KVLKAAA
Physicochemical Analysis
C32H61N9O8
RNDCEQGHIMFPSTWY
A
699.89
10.60
2
0
5
+2
0.98
0.800
140.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
7
C32H61N9O8
699.89
10.60
+2
0.98
0.800
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>100 µM
Hemolytic Cytotoxic
50% Hemolysis | >100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
In vitro discriminative antipseudomonal properties resulting from acyl substitution of N-terminal sequence of dermaseptin s4 derivatives. | Chem Biol | 2007
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
27 µM
Hemolytic Cytotoxic
50% Hemolysis | 27 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
In vitro discriminative antipseudomonal properties resulting from acyl substitution of N-terminal sequence of dermaseptin s4 derivatives. | Chem Biol | 2007
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis