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Peptide record

TPDB22410

Antibacterial Anticancer Antifungal Cell-penetrating Peptides Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB22410
Antibacterial Anticancer Antifungal Cell-penetrating Peptides Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF pep-lab dbAMP CellPPD-MOD CPPsite3.0
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, ACP740 _ACP240, AntiCP 2.0, and other sources, with an available 3D structural model.
Sequence
KVKVKVKVPPTKVKVKVK
Physicochemical Analysis
C97H182N26O20
ARNDCEQGHILMFSWY
K
2032.67
11.36
8
0
7
+8
9.45
-0.317
112.78
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
8
K
0
M
0
F
2
P
0
S
1
T
0
W
0
Y
7
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 8 M: 0 F: 0 P: 2 S: 0 T: 1 W: 0 Y: 0 V: 7
Chemical Descriptors
18
C97H182N26O20
2032.67
11.36
+8
9.45
-0.317
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>1000 µM
Hemolytic Cytotoxic
50% Hemolysis | >1000 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Anticancer ?-hairpin peptides: membrane-induced folding triggers activity. | J Am Chem Soc | 2012
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
J Am Chem Soc. 2012 Apr 11 134(14):6210-7.