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Peptide record

TPDB22397

Antibacterial Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB22397
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 11-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
KVARFLKKFFR
Physicochemical Analysis
C71H114N20O12
NDCEQGHIMPSTWY
KF
1439.81
12.43
5
0
6
+5
0.54
-0.227
70.91
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
1
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
3
K
0
M
3
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 3 M: 0 F: 3 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
11
C71H114N20O12
1439.81
12.43
+5
0.54
-0.227
Evidence Records 1 records
Evidence 1 Activity

Activity

20% Hemolysis
Toxicity
>2000 µg/mL
Hemolytic Cytotoxic
20% Hemolysis | >2000 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Machine learning designs non-hemolytic antimicrobial peptides. | Chem Sci | 2021