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Peptide record

TPDB22377

Antibacterial Hemolysis Toxicity standard
57 amino acids
Basic Information
3D PDB MODEL
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TPDB22377
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 57-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from Peptipedia, HemoPI, Hemolytic2, and other sources, with an available 3D structural model.
Sequence
KSTVGQKLKKKLNQAVDKVKEVLNKSEYMCPVVSSFCKQHCARLGKSGQCDLLECIC
Physicochemical Analysis
C272H462N78O81S7
W
K
6345.55
9.16
12
5
18
+6
17.29
-0.319
81.93
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1865
29.39
19
Residue Composition
number
2
A
1
R
2
N
2
D
6
C
3
E
4
Q
3
G
1
H
1
I
6
L
10
K
1
M
1
F
1
P
5
S
1
T
0
W
1
Y
6
V
Amino Acid Distribution
A: 2 R: 1 N: 2 D: 2 C: 6 E: 3 Q: 4 G: 3 H: 1 I: 1 L: 6 K: 10 M: 1 F: 1 P: 1 S: 5 T: 1 W: 0 Y: 1 V: 6
Chemical Descriptors
57
C272H462N78O81S7
6345.55
9.16
+6
17.29
-0.319
Evidence Records 2 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
0.2 µM
Hemolytic Cytotoxic
100% Hemolysis | 0.2 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cytolytic and K+ channel blocking activities of beta-KTx and scorpine-like peptides purified from scorpion venoms. | Cell Mol Life Sci | 2008
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis