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Peptide record

TPDB22374

Antibacterial Antifungal Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB22374
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and CAFPdb, with an available 3D structural model.
Sequence
KTKKKFLKKT
Physicochemical Analysis
C59H108N16O13
ARNDCEQGHIMPSWYV
K
1249.61
11.21
6
0
2
+6
4.53
-1.820
39.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
6
K
0
M
1
F
0
P
0
S
2
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 6 M: 0 F: 1 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C59H108N16O13
1249.61
11.21
+6
4.53
-1.820
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Polymyxin B is anti-film of P. mirabilis ( Liu MC et al., 2012 ). BInds LPS:anti-inflammatory by supressing TNF-alpha released from murine RAW 264.7 cells and in vivo animal model:mouse:sepsis (see ref for AP3643). It also has antifungal activity in vivo ( Zhai and Lin 2013 ).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

CAFPdb

Other

Polymyxin B is anti-film of P. mirabilis ( Liu MC et al., 2012 ). BInds LPS:anti-inflammatory by supressing TNF-alpha released from murine RAW 264.7 cells and in vivo animal model:mouse:sepsis (see ref for AP3643). It also has antifungal activity in vivo ( Zhai and Lin 2013 ).