Peptide record

TPDB22370

Antibacterial Anticancer Antifungal Antiparasitic standard
46 amino acids
Basic Information
3D PDB MODEL
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TPDB22370
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb DRAMP dbAMP i2APP
standard
No
A 46-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, AntiCP 2.0, iACP-DRLF, and other sources, with an available 3D structural model.
Sequence
KTCEHLADTYRGVCFTNASCDDHCKNKAHLISGTCHNWKCFCTQNC
Physicochemical Analysis
C216H329N67O68S8
MP
C
5208.88
7.53
9
4
11
+1
8.72
-0.548
38.26
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
7490
143.79
21
Residue Composition
number
3
A
1
R
4
N
3
D
8
C
1
E
1
Q
2
G
4
H
1
I
2
L
4
K
0
M
2
F
0
P
2
S
5
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 3 R: 1 N: 4 D: 3 C: 8 E: 1 Q: 1 G: 2 H: 4 I: 1 L: 2 K: 4 M: 0 F: 2 P: 0 S: 2 T: 5 W: 1 Y: 1 V: 1
Chemical Descriptors
46
C216H329N67O68S8
5208.88
7.53
+1
8.72
-0.548
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
Antibacterial
0.04-21 µg/mL

Target

N. crassa

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
DRAMP antibacterial activity supported by MIC records against bacterial target organisms. dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against fungal A. niger, A. versicolor, F. moniliforme, F. solani, N. crassa (IC50 0.04-21 ug/ml), C. albicans.
Evidence 2 Activity

Activity

IC50
Antifungal
0.04-21 µg/mL

Target

N. crassa

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
DRAMP antifungal activity supported by activity records against fungal target organisms. dbAMP classified under the Anti-fungal function class.
Active against fungal A. niger, A. versicolor, F. moniliforme, F. solani, N. crassa (IC50 0.04-21 ug/ml), C. albicans.
Evidence 3 Activity

Activity

IC50
Antiparasitic
0.04-21 µg/mL

Target

N. crassa

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against fungal A. niger, A. versicolor, F. moniliforme, F. solani, N. crassa (IC50 0.04-21 ug/ml), C. albicans.