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Peptide record

TPDB22350

Antibacterial Antifungal Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB22350
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Sequence
KSKKPLFKIWKCVENVCVLWYK
Physicochemical Analysis
C132H207N31O28S2
ARDQGHMT
K
2740.41
10.12
6
1
10
+5
1.49
-0.155
92.73
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
12615
460.33
5
Residue Composition
number
0
A
0
R
1
N
0
D
2
C
1
E
0
Q
0
G
0
H
1
I
2
L
6
K
0
M
1
F
1
P
1
S
0
T
2
W
1
Y
3
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 2 E: 1 Q: 0 G: 0 H: 0 I: 1 L: 2 K: 6 M: 0 F: 1 P: 1 S: 1 T: 0 W: 2 Y: 1 V: 3
Chemical Descriptors
22
C132H207N31O28S2
2740.41
10.12
+5
1.49
-0.155
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Cell death
Toxicity
25 µM
Cytotoxic
10% Cell death | 25 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Symbiotic NCR Peptide Fragments Affect the Viability, Morphology and Biofilm Formation of Candida Species. | Int J Mol Sci | 2021
Evidence 2 Activity

Activity

5% Cell death
Toxicity
25 µM
Cytotoxic
5% Cell death | 25 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Symbiotic NCR Peptide Fragments Affect the Viability, Morphology and Biofilm Formation of Candida Species. | Int J Mol Sci | 2021