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Peptide record

TPDB22306

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB22306
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia Antifungipept CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
KRLFKELLFSLRKY
Physicochemical Analysis
C89H145N23O19
ANDCQGHIMPTWV
L
1841.27
10.89
5
1
7
+4
1.30
-0.393
111.43
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
80.92
2
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
1
E
0
Q
0
G
0
H
0
I
4
L
3
K
0
M
2
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 3 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
14
C89H145N23O19
1841.27
10.89
+4
1.30
-0.393
Evidence Records 5 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
89±12 µM
Hemolytic Cytotoxic
50% Hemolysis | 89±12 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A critical comparison of the hemolytic and fungicidal activities of cationic antimicrobial peptides | FEBS Lett | 1999
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
>108 µM
Hemolytic Cytotoxic
50% Hemolysis | >108 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A critical comparison of the hemolytic and fungicidal activities of cationic antimicrobial peptides | FEBS Lett | 1999
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
73±2.0 µM
Hemolytic Cytotoxic
50% Hemolysis | 73±2.0 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A critical comparison of the hemolytic and fungicidal activities of cationic antimicrobial peptides | FEBS Lett | 1999
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
59±0.1 µM
Hemolytic Cytotoxic
50% Hemolysis | 59±0.1 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A critical comparison of the hemolytic and fungicidal activities of cationic antimicrobial peptides | FEBS Lett | 1999
Evidence 5 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis