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Peptide record

TPDB22295

Antibacterial Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB22295
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
KRLWKIRQRIAK
Physicochemical Analysis
C73H130N26O14
NDCEGHMFPSTYV
RK
1596.00
12.71
6
0
5
+6
2.78
-1.250
105.83
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
344.61
1
Residue Composition
number
1
A
3
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
2
I
1
L
3
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 2 L: 1 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
12
C73H130N26O14
1596.00
12.71
+6
2.78
-1.250
Evidence Records 1 records
Evidence 1 Activity

Activity

20% Hemolysis
Toxicity
>2000 µg/mL
Hemolytic Cytotoxic
20% Hemolysis | >2000 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Machine learning designs non-hemolytic antimicrobial peptides. | Chem Sci | 2021