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Peptide record

TPDB22287

Antibacterial Antiviral Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB22287
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
KRKRAVKRVGRRLKKLARKIARLGVAKLAGLRAVKLF
Physicochemical Analysis
C191H355N69O38
NDCEQHMPSTWY
RK
4226.36
13.25
16
0
18
+16
8.89
-0.289
121.35
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
6
A
8
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
1
I
6
L
8
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 6 R: 8 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 6 K: 8 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 4
Chemical Descriptors
37
C191H355N69O38
4226.36
13.25
+16
8.89
-0.289
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
5.26 µM
Cytotoxic
50% Cytotoxicity | 5.26 | µM | target cell: Feline kidney epithelial CRFK cells

Target

Feline kidney epithelial CRFK cells

Source & Reference

NA
DBAASP
Inhibitory activity of synthetic peptide antibiotics on feline immunodeficiency virus infectivity in vitro. | J Virol | 2002
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.12208971]CrFK cell:TC50=5.26 µM.

Source & Reference

NA
DRAMP
J Virol. 2002 Oct 76(19):9952-61.