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Peptide record

TPDB22273

Antibacterial Antifungal Toxicity standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB22273
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
standard
No
A 3-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Sequence
KRK
Physicochemical Analysis
C18H38N8O4
ANDCEQGHILMFPSTWYV
K
430.55
11.64
3
0
0
+3
2.79
-4.100
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
3
C18H38N8O4
430.55
11.64
+3
2.79
-4.100
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
Toxicity
2.3±0.4 µg/mL
Cytotoxic
IC50 | 2.3±0.4 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
In Vitro Evaluation of Cytotoxicity and Permeation Study on Lysine- and Arginine-Based Lipopeptides with Proven Antimicrobial Activity. | Molecules | 2017