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Peptide record

TPDB22267

Antibacterial Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB22267
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
KRIVKWIKKFLR
Physicochemical Analysis
C79H135N23O13
ANDCEQGHMPSTY
K
1615.09
12.44
6
0
6
+6
1.49
-0.475
121.67
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
340.54
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
1
L
4
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 4 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
12
C79H135N23O13
1615.09
12.44
+6
1.49
-0.475
Evidence Records 2 records
Evidence 1 Activity

Activity

MIC
Antibacterial
96.7 µM

Target

S. Gordonii

Source & Reference

NA

Other

weakly active against S. Gordonii (MIC 96.7 uM). Warning: other bacteria not tested. It inhbited formation of biofilms:bacteria. It suppr
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Mouse osteoblastic cells MC3T3-E1

Target

Mouse osteoblastic cells MC3T3-E1

Source & Reference

NA
DBAASP
Antibacterial and Anti-Inflammatory Properties of a Novel Antimicrobial Peptide Derived from LL-37. | Antibiotics (Basel) | 2022