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Peptide record

TPDB22266

Antibacterial standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB22266
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 5-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
KRIRL
Physicochemical Analysis
C30H60N12O6
ANDCEQGHMFPSTWYV
R
684.88
12.41
3
0
2
+3
1.74
-0.920
156.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C30H60N12O6
684.88
12.41
+3
1.74
-0.920
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

B. subtilis 168 1A1

Source & Reference

NA

Other

active against B. subtilis 168 1A1 (MIC 4 ug/ml), E. faecium Com15 (MIC 8 ug/ml), S. aureus USA300 (MIC 8 ug/ml), E. coli DH5alpha (MIC 16
Evidence 2 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

E. faecium Com15

Source & Reference

NA

Other

active against B. subtilis 168 1A1 (MIC 4 ug/ml), E. faecium Com15 (MIC 8 ug/ml), S. aureus USA300 (MIC 8 ug/ml), E. coli DH5alpha (MIC 16 ug/ml), K. pneumoniae ATCC 1003
Evidence 3 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

Staphylococcus aureus USA300

Source & Reference

NA

Other

active against B. subtilis 168 1A1 (MIC 4 ug/ml), E. faecium Com15 (MIC 8 ug/ml), S. aureus USA300 (MIC 8 ug/ml), E. coli DH5alpha (MIC 16 ug/ml), K. pneumoniae ATCC 10031 (MIC 8 ug/ml), A. baumannii AT
Evidence 4 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

Escherichia coli DH5alpha

Source & Reference

NA

Other

is 168 1A1 (MIC 4 ug/ml), E. faecium Com15 (MIC 8 ug/ml), S. aureus USA300 (MIC 8 ug/ml), E. coli DH5alpha (MIC 16 ug/ml), K. pneumoniae ATCC 10031 (MIC 8 ug/ml), A. baumannii ATCC 17978 (MIC 32 ug/ml), P. aerug
Evidence 5 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

Klebsiella pneumoniae ATCC 10031

Source & Reference

NA

Other

ium Com15 (MIC 8 ug/ml), S. aureus USA300 (MIC 8 ug/ml), E. coli DH5alpha (MIC 16 ug/ml), K. pneumoniae ATCC 10031 (MIC 8 ug/ml), A. baumannii ATCC 17978 (MIC 32 ug/ml), P. aeruginosa PAO1 (MI 16 ug/ml), E. cloacae ATC
Evidence 6 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

A. baumannii ATCC 17978

Source & Reference

NA

Other

0 (MIC 8 ug/ml), E. coli DH5alpha (MIC 16 ug/ml), K. pneumoniae ATCC 10031 (MIC 8 ug/ml), A. baumannii ATCC 17978 (MIC 32 ug/ml), P. aeruginosa PAO1 (MI 16 ug/ml), E. cloacae ATCC 14037 (MIC 64 ug/ml), M. tuberculosis
Evidence 7 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Enterobacter cloacae ATCC 14037

Source & Reference

NA

Other

(MIC 8 ug/ml), A. baumannii ATCC 17978 (MIC 32 ug/ml), P. aeruginosa PAO1 (MI 16 ug/ml), E. cloacae ATCC 14037 (MIC 64 ug/ml), M. tuberculosis H37RV (MIC 6 ug/ml). This peptide shows the broadest activity spectrum i
Evidence 8 Activity

Activity

MIC
Antibacterial
6 µg/mL

Target

M. tuberculosis H37RV

Source & Reference

NA

Other

8 (MIC 32 ug/ml), P. aeruginosa PAO1 (MI 16 ug/ml), E. cloacae ATCC 14037 (MIC 64 ug/ml), M. tuberculosis H37RV (MIC 6 ug/ml). This peptide shows the broadest activity spectrum in this family of peptides. MOA:bacter