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Peptide record

TPDB22265

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB22265
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
KRIRKWVRRILKKL
Physicochemical Analysis
C88H161N31O15
ANDCEQGHMFPSTY
RK
1893.45
12.89
8
0
6
+8
3.68
-0.979
132.14
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
290.48
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
2
L
4
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 2 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
14
C88H161N31O15
1893.45
12.89
+8
3.68
-0.979
Evidence Records 1 records
Evidence 1 Activity

Activity

20% Hemolysis
Toxicity
250 µg/mL
Hemolytic Cytotoxic
20% Hemolysis | 250 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Machine learning designs non-hemolytic antimicrobial peptides. | Chem Sci | 2021