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Peptide record

TPDB22263

Antibacterial Antifungal standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB22263
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 18-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
KRHHGYKRKFHEKHHSHR
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C106H161N43O23
ANDCQILMPTWV
H
2405.72
11.55
13
1
2
+7
5.63
-2.861
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
0.62
2
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
1
E
0
Q
1
G
6
H
0
I
0
L
4
K
0
M
1
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 6 I: 0 L: 0 K: 4 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
18 reviewed residue count
C106H161N43O23 sequence-only estimate (linear, free termini)
2405.72 sequence-only estimate (linear, free termini)
11.55 sequence-only estimate (linear, free termini)
+7 sequence-only estimate (linear, free termini)
5.63 sequence-only estimate (linear, free termini)
-2.861 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against C. albicans (LD50 10.7 ug/ml LD90 24.8 ug/ml).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against C. albicans (LD50 10.7 ug/ml LD90 24.8 ug/ml).