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Peptide record

TPDB22259

Antibacterial standard
22 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB22259
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 22-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
KRGTGWFATITDDCPNSVFVCC
Physicochemical Analysis
C105H158N28O32S3
EQHLMY
CT
2420.76
6.01
2
2
7
-0
0.53
0.123
48.64
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5625
232.37
8
Residue Composition
number
1
A
1
R
1
N
2
D
3
C
0
E
0
Q
2
G
0
H
1
I
0
L
1
K
0
M
2
F
1
P
1
S
3
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 2 C: 3 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 0 K: 1 M: 0 F: 2 P: 1 S: 1 T: 3 W: 1 Y: 0 V: 2
Chemical Descriptors
22
C105H158N28O32S3
2420.76
6.01
-0
0.53
0.123
Evidence Records 21 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2 µg/mL

Target

M. luteus ATCC 10240

Source & Reference

NA

Other

Active against M. luteus ATCC 10240 (MIC 2 ug/ml), C. accolens ATCC 49725 (MIC 8 ug/ml), C. accolens KPL 1818 (MIC 16 ug/ml), C. accolens K
Evidence 2 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

C. accolens ATCC 49725

Source & Reference

NA

Other

Active against M. luteus ATCC 10240 (MIC 2 ug/ml), C. accolens ATCC 49725 (MIC 8 ug/ml), C. accolens KPL 1818 (MIC 16 ug/ml), C. accolens KPL 2060 (MIC 8 ug/ml), C. accolens KPL
Evidence 3 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

C. accolens KPL 1818

Source & Reference

NA

Other

Active against M. luteus ATCC 10240 (MIC 2 ug/ml), C. accolens ATCC 49725 (MIC 8 ug/ml), C. accolens KPL 1818 (MIC 16 ug/ml), C. accolens KPL 2060 (MIC 8 ug/ml), C. accolens KPL 2061 (MIC 16 ug/ml), C. pseudodiphth
Evidence 4 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

C. accolens KPL 2060

Source & Reference

NA

Other

(MIC 2 ug/ml), C. accolens ATCC 49725 (MIC 8 ug/ml), C. accolens KPL 1818 (MIC 16 ug/ml), C. accolens KPL 2060 (MIC 8 ug/ml), C. accolens KPL 2061 (MIC 16 ug/ml), C. pseudodiphtheriticum KPL 1989 (MIC 8 ug/ml), C.
Evidence 5 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

C. accolens KPL 2061

Source & Reference

NA

Other

5 (MIC 8 ug/ml), C. accolens KPL 1818 (MIC 16 ug/ml), C. accolens KPL 2060 (MIC 8 ug/ml), C. accolens KPL 2061 (MIC 16 ug/ml), C. pseudodiphtheriticum KPL 1989 (MIC 8 ug/ml), C. striatum KPL 1959 (MIC 32 ug/ml), C.
Evidence 6 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

C. pseudodiphtheriticum KPL 1989

Source & Reference

NA

Other

(MIC 16 ug/ml), C. accolens KPL 2060 (MIC 8 ug/ml), C. accolens KPL 2061 (MIC 16 ug/ml), C. pseudodiphtheriticum KPL 1989 (MIC 8 ug/ml), C. striatum KPL 1959 (MIC 32 ug/ml), C. accolens KPL 1855 (MIC 16 ug/ml), S. pneumoniae
Evidence 7 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

C. striatum KPL 1959

Source & Reference

NA

Other

ml), C. accolens KPL 2061 (MIC 16 ug/ml), C. pseudodiphtheriticum KPL 1989 (MIC 8 ug/ml), C. striatum KPL 1959 (MIC 32 ug/ml), C. accolens KPL 1855 (MIC 16 ug/ml), S. pneumoniae ATCC 27336 (MIC 32 ug/ml), (MIC 2 ug/
Evidence 8 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

C. accolens KPL 1855

Source & Reference

NA

Other

ml), C. pseudodiphtheriticum KPL 1989 (MIC 8 ug/ml), C. striatum KPL 1959 (MIC 32 ug/ml), C. accolens KPL 1855 (MIC 16 ug/ml), S. pneumoniae ATCC 27336 (MIC 32 ug/ml), (MIC 2 ug/ml), S. pneumoniae AI8 (MIC 32 ug/ml)
Evidence 9 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

S. pneumoniae ATCC 27336

Source & Reference

NA

Other

(MIC 8 ug/ml), C. striatum KPL 1959 (MIC 32 ug/ml), C. accolens KPL 1855 (MIC 16 ug/ml), S. pneumoniae ATCC 27336 (MIC 32 ug/ml), (MIC 2 ug/ml), S. pneumoniae AI8 (MIC 32 ug/ml), S. pneumoniae AI11 (MIC 16 ug/ml), S. p
Evidence 10 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

S. pneumoniae AI8

Source & Reference

NA

Other

accolens KPL 1855 (MIC 16 ug/ml), S. pneumoniae ATCC 27336 (MIC 32 ug/ml), (MIC 2 ug/ml), S. pneumoniae AI8 (MIC 32 ug/ml), S. pneumoniae AI11 (MIC 16 ug/ml), S. pneumoniae AI14 (MIC 16 ug/ml), S.pneumoniae AI6 (
Evidence 11 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

S. pneumoniae AI11

Source & Reference

NA

Other

S. pneumoniae ATCC 27336 (MIC 32 ug/ml), (MIC 2 ug/ml), S. pneumoniae AI8 (MIC 32 ug/ml), S. pneumoniae AI11 (MIC 16 ug/ml), S. pneumoniae AI14 (MIC 16 ug/ml), S.pneumoniae AI6 (MIC 128 ug/ml), S.pneumoniae AI7 (M
Evidence 12 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

S. pneumoniae AI14

Source & Reference

NA

Other

/ml), (MIC 2 ug/ml), S. pneumoniae AI8 (MIC 32 ug/ml), S. pneumoniae AI11 (MIC 16 ug/ml), S. pneumoniae AI14 (MIC 16 ug/ml), S.pneumoniae AI6 (MIC 128 ug/ml), S.pneumoniae AI7 (MIC 128 ug/ml), S.mutans JH1140 (MIC
Evidence 13 Activity

Activity

MIC
Antibacterial
128 µg/mL

Target

S.pneumoniae AI6

Source & Reference

NA

Other

AI8 (MIC 32 ug/ml), S. pneumoniae AI11 (MIC 16 ug/ml), S. pneumoniae AI14 (MIC 16 ug/ml), S.pneumoniae AI6 (MIC 128 ug/ml), S.pneumoniae AI7 (MIC 128 ug/ml), S.mutans JH1140 (MIC >128 ug/ml), (MIC 16 ug/ml), S. s
Evidence 14 Activity

Activity

MIC
Antibacterial
128 µg/mL

Target

S.pneumoniae AI7

Source & Reference

NA

Other

AI11 (MIC 16 ug/ml), S. pneumoniae AI14 (MIC 16 ug/ml), S.pneumoniae AI6 (MIC 128 ug/ml), S.pneumoniae AI7 (MIC 128 ug/ml), S.mutans JH1140 (MIC >128 ug/ml), (MIC 16 ug/ml), S. salivarius HS0302 (MIC 64 ug/ml), B
Evidence 15 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

S.mutans JH1140

Source & Reference

NA

Other

AI14 (MIC 16 ug/ml), S.pneumoniae AI6 (MIC 128 ug/ml), S.pneumoniae AI7 (MIC 128 ug/ml), S.mutans JH1140 (MIC >128 ug/ml), (MIC 16 ug/ml), S. salivarius HS0302 (MIC 64 ug/ml), B.subtilis PY79 (MIC >128 ug/ml), B
Evidence 16 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

S. salivarius HS0302

Source & Reference

NA

Other

/ml), S.pneumoniae AI7 (MIC 128 ug/ml), S.mutans JH1140 (MIC >128 ug/ml), (MIC 16 ug/ml), S. salivarius HS0302 (MIC 64 ug/ml), B.subtilis PY79 (MIC >128 ug/ml), B.megaterium ATCC 14581 (MIC >128 ug/ml), S.epidermidi
Evidence 17 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

B.subtilis PY79

Source & Reference

NA

Other

), S.mutans JH1140 (MIC >128 ug/ml), (MIC 16 ug/ml), S. salivarius HS0302 (MIC 64 ug/ml), B.subtilis PY79 (MIC >128 ug/ml), B.megaterium ATCC 14581 (MIC >128 ug/ml), S.epidermidis ERIN 30713 (MIC >128 ug/ml), S.a
Evidence 18 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

B.megaterium ATCC 14581

Source & Reference

NA

Other

), (MIC 16 ug/ml), S. salivarius HS0302 (MIC 64 ug/ml), B.subtilis PY79 (MIC >128 ug/ml), B.megaterium ATCC 14581 (MIC >128 ug/ml), S.epidermidis ERIN 30713 (MIC >128 ug/ml), S.aureus ATCC 25923 (MIC >128 ug/ml), and E.f
Evidence 19 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

S.epidermidis ERIN 30713

Source & Reference

NA

Other

IC 64 ug/ml), B.subtilis PY79 (MIC >128 ug/ml), B.megaterium ATCC 14581 (MIC >128 ug/ml), S.epidermidis ERIN 30713 (MIC >128 ug/ml), S.aureus ATCC 25923 (MIC >128 ug/ml), and E.faecalis ERIN 30002 (MIC >128 ug/ml) ( Geng
Evidence 20 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

S.aureus ATCC 25923

Source & Reference

NA

Other

ml), B.megaterium ATCC 14581 (MIC >128 ug/ml), S.epidermidis ERIN 30713 (MIC >128 ug/ml), S.aureus ATCC 25923 (MIC >128 ug/ml), and E.faecalis ERIN 30002 (MIC >128 ug/ml) ( Geng et al., 2018 ).
Evidence 21 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

Enterococcus faecalis ERIN 30002

Source & Reference

NA

Other

ml), S.epidermidis ERIN 30713 (MIC >128 ug/ml), S.aureus ATCC 25923 (MIC >128 ug/ml), and E.faecalis ERIN 30002 (MIC >128 ug/ml) ( Geng et al., 2018 ).