Back to search

Peptide record

TPDB22256

Antibacterial Antifungal standard
31 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB22256
Antibacterial Antifungal
Anti-infective peptides
Peptipedia AFP-GFuse CAFPdb
standard
No
A 31-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, AFP-GFuse, and CAFPdb, with an available 3D structural model.
Sequence
KRGGIWKLIRPLGRGAGRILRHFHIDFCGNC
Physicochemical Analysis
C159H256N54O35S2
EQMSTYV
G
3548.24
11.85
9
1
11
+6
2.43
-0.219
91.29
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5625
158.53
3
Residue Composition
number
1
A
5
R
1
N
1
D
2
C
0
E
0
Q
6
G
2
H
4
I
3
L
2
K
0
M
2
F
1
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 5 N: 1 D: 1 C: 2 E: 0 Q: 0 G: 6 H: 2 I: 4 L: 3 K: 2 M: 0 F: 2 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
31
C159H256N54O35S2
3548.24
11.85
+6
2.43
-0.219
Evidence Records 16 records
Evidence 1 Activity

Activity

MIC
Antibacterial
16-64 µg/mL

Target

Escherichia coli ATCC25922

Source & Reference

NA

Other

tion-adjusted Mueller Hinton Broth, active against P-aeruginosa ATCC27853 (MIC>64 ug/ml), E. coli ATCC25922 (MIC 16-64 ug/ml), S. aureus MRSA (8-16 ug/ml), S-pneumoniae ATCC49619 (MIC>64 ug/ml), S. pyogenes ATCC1961
Evidence 2 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Streptococcus pyogenes ATCC19615

Source & Reference

NA

Other

22 (MIC 16-64 ug/ml), S. aureus MRSA (8-16 ug/ml), S-pneumoniae ATCC49619 (MIC>64 ug/ml), S. pyogenes ATCC19615 (MIC 64 ug/ml), S. agalactiae ATCC12386 (MIC 64 ug/ml), S-dysgalactiae (MIC>64 ug/ml), S-lutetiensis (MI
Evidence 3 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Streptococcus agalactiae ATCC12386

Source & Reference

NA

Other

8-16 ug/ml), S-pneumoniae ATCC49619 (MIC>64 ug/ml), S. pyogenes ATCC19615 (MIC 64 ug/ml), S. agalactiae ATCC12386 (MIC 64 ug/ml), S-dysgalactiae (MIC>64 ug/ml), S-lutetiensis (MIC>64 ug/ml), S-equi (MIC>64 ug/ml), S-or
Evidence 4 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

S. salivarius

Source & Reference

NA

Other

>64 ug/ml), S-lutetiensis (MIC>64 ug/ml), S-equi (MIC>64 ug/ml), S-oralis (MIC>64 ug/ml), S. salivarius (MIC 64 ug/ml), S. mutans (MIC>64 ug/ml), L. monocytogenes (MIC 64 ug/ml), P-multocida (MIC>64 ug/ml), K
Evidence 5 Activity

Activity

MIC
Antibacterial
>64 µg/mL

Target

S. mutans

Source & Reference

NA

Other

>64 ug/ml), S-equi (MIC>64 ug/ml), S-oralis (MIC>64 ug/ml), S. salivarius (MIC 64 ug/ml), S. mutans (MIC>64 ug/ml), L. monocytogenes (MIC 64 ug/ml), P-multocida (MIC>64 ug/ml), K-pneumoniae (MIC >64 ug/ml
Evidence 6 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

L. monocytogenes

Source & Reference

NA

Other

ug/ml), S-oralis (MIC>64 ug/ml), S. salivarius (MIC 64 ug/ml), S. mutans (MIC>64 ug/ml), L. monocytogenes (MIC 64 ug/ml), P-multocida (MIC>64 ug/ml), K-pneumoniae (MIC >64 ug/ml), C. parapsilosis ATCC 22019 (MI
Evidence 7 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

C. parapsilosis ATCC 22019

Source & Reference

NA

Other

. monocytogenes (MIC 64 ug/ml), P-multocida (MIC>64 ug/ml), K-pneumoniae (MIC >64 ug/ml), C. parapsilosis ATCC 22019 (MIC 32 ug/ml), C. krusei ATCC 6258 (MIC 64 ug/ml), C-glabrata (MIC >64 ug/ml), and C-albicans (MIC >64
Evidence 8 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

C. krusei ATCC 6258

Source & Reference

NA

Other

(MIC>64 ug/ml), K-pneumoniae (MIC >64 ug/ml), C. parapsilosis ATCC 22019 (MIC 32 ug/ml), C. krusei ATCC 6258 (MIC 64 ug/ml), C-glabrata (MIC >64 ug/ml), and C-albicans (MIC >64 ug/ml). In addition, PhciCath5 inact
Evidence 9 Activity

Activity

MIC
Antifungal
16-64 µg/mL

Target

Escherichia coli ATCC25922

Source & Reference

CAFPdb

Other

tion-adjusted Mueller Hinton Broth, active against P-aeruginosa ATCC27853 (MIC>64 ug/ml), E. coli ATCC25922 (MIC 16-64 ug/ml), S. aureus MRSA (8-16 ug/ml), S-pneumoniae ATCC49619 (MIC>64 ug/ml), S. pyogenes ATCC1961
Evidence 10 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

Streptococcus pyogenes ATCC19615

Source & Reference

CAFPdb

Other

22 (MIC 16-64 ug/ml), S. aureus MRSA (8-16 ug/ml), S-pneumoniae ATCC49619 (MIC>64 ug/ml), S. pyogenes ATCC19615 (MIC 64 ug/ml), S. agalactiae ATCC12386 (MIC 64 ug/ml), S-dysgalactiae (MIC>64 ug/ml), S-lutetiensis (MI
Evidence 11 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

Streptococcus agalactiae ATCC12386

Source & Reference

CAFPdb

Other

8-16 ug/ml), S-pneumoniae ATCC49619 (MIC>64 ug/ml), S. pyogenes ATCC19615 (MIC 64 ug/ml), S. agalactiae ATCC12386 (MIC 64 ug/ml), S-dysgalactiae (MIC>64 ug/ml), S-lutetiensis (MIC>64 ug/ml), S-equi (MIC>64 ug/ml), S-or
Evidence 12 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

S. salivarius

Source & Reference

CAFPdb

Other

>64 ug/ml), S-lutetiensis (MIC>64 ug/ml), S-equi (MIC>64 ug/ml), S-oralis (MIC>64 ug/ml), S. salivarius (MIC 64 ug/ml), S. mutans (MIC>64 ug/ml), L. monocytogenes (MIC 64 ug/ml), P-multocida (MIC>64 ug/ml), K
Evidence 13 Activity

Activity

MIC
Antifungal
>64 µg/mL

Target

S. mutans

Source & Reference

CAFPdb

Other

>64 ug/ml), S-equi (MIC>64 ug/ml), S-oralis (MIC>64 ug/ml), S. salivarius (MIC 64 ug/ml), S. mutans (MIC>64 ug/ml), L. monocytogenes (MIC 64 ug/ml), P-multocida (MIC>64 ug/ml), K-pneumoniae (MIC >64 ug/ml
Evidence 14 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

L. monocytogenes

Source & Reference

CAFPdb

Other

ug/ml), S-oralis (MIC>64 ug/ml), S. salivarius (MIC 64 ug/ml), S. mutans (MIC>64 ug/ml), L. monocytogenes (MIC 64 ug/ml), P-multocida (MIC>64 ug/ml), K-pneumoniae (MIC >64 ug/ml), C. parapsilosis ATCC 22019 (MI
Evidence 15 Activity

Activity

MIC
Antifungal
32 µg/mL

Target

C. parapsilosis ATCC 22019

Source & Reference

CAFPdb

Other

. monocytogenes (MIC 64 ug/ml), P-multocida (MIC>64 ug/ml), K-pneumoniae (MIC >64 ug/ml), C. parapsilosis ATCC 22019 (MIC 32 ug/ml), C. krusei ATCC 6258 (MIC 64 ug/ml), C-glabrata (MIC >64 ug/ml), and C-albicans (MIC >64
Evidence 16 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

C. krusei ATCC 6258

Source & Reference

CAFPdb

Other

(MIC>64 ug/ml), K-pneumoniae (MIC >64 ug/ml), C. parapsilosis ATCC 22019 (MIC 32 ug/ml), C. krusei ATCC 6258 (MIC 64 ug/ml), C-glabrata (MIC >64 ug/ml), and C-albicans (MIC >64 ug/ml). In addition, PhciCath5 inact