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Peptide record

TPDB22253

Cathelicidin Hydrostatin-AMP2 Antibacterial Toxicity standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB22253
Cathelicidin Hydrostatin-AMP2
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia DBAASP
standard
No
A 34-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia and DBAASP, with an available 3D structural model.
Sequence
KRFKKFFKKLRKSVKKRVKKFFKKPKVIGVSIPF
Physicochemical Analysis
C206H344N56O37
ANDCEQHMTWY
K
4197.35
12.75
16
0
13
+16
8.79
-0.676
68.53
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
1
L
13
K
0
M
6
F
2
P
2
S
0
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 1 K: 13 M: 0 F: 6 P: 2 S: 2 T: 0 W: 0 Y: 0 V: 4
Chemical Descriptors
34
C206H344N56O37
4197.35
12.75
+16
8.79
-0.676
Evidence Records 4 records
Evidence 1 Activity

Activity

8.08% Cell death
Toxicity
32 µg/mL
Cytotoxic
8.08% Cell death | 32 | µg/mL | target cell: Mouse fibroblasts L929

Target

Mouse fibroblasts L929

Source & Reference

NA
DBAASP
Identification and Characterization of a Novel Cathelicidin from Hydrophis cyanocinctus with Antimicrobial and Anti-Inflammatory Activity | Molecules | 2023
Evidence 2 Activity

Activity

5.89% Cell death
Toxicity
32 µg/mL
Cytotoxic
5.89% Cell death | 32 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Identification and Characterization of a Novel Cathelicidin from Hydrophis cyanocinctus with Antimicrobial and Anti-Inflammatory Activity | Molecules | 2023
Evidence 3 Activity

Activity

4.6% Hemolysis
Toxicity
250 µg/mL
Hemolytic Cytotoxic
4.6% Hemolysis | 250 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and Characterization of a Novel Cathelicidin from Hydrophis cyanocinctus with Antimicrobial and Anti-Inflammatory Activity | Molecules | 2023
Evidence 4 Activity

Target

Cutibacterium acnes

Source & Reference

DBAASP