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Peptide record

TPDB22251

Antibacterial Antiparasitic Toxicity standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB22251
Antibacterial Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Antiparasitic, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
KRFKKFFKKLKNSVKKRVKFFFRKPRVIGVTFP
Physicochemical Analysis
C202H326N56O37
ADCEQHMWY
K
4131.16
12.90
14
0
13
+14
6.24
-0.633
58.79
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
0
A
4
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
1
L
10
K
0
M
7
F
2
P
1
S
1
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 0 R: 4 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 1 K: 10 M: 0 F: 7 P: 2 S: 1 T: 1 W: 0 Y: 0 V: 4
Chemical Descriptors
33
C202H326N56O37
4131.16
12.90
+14
6.24
-0.633
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
3.51±0.74 µM
Cytotoxic
50% Cytotoxicity | 3.51±0.74 | µM | target cell: Murine macrophage cells J774

Target

Murine macrophage cells J774

Source & Reference

NA
DBAASP
Mechanistic Insights into the Leishmanicidal and Bactericidal Activities of Batroxicidin, a Cathelicidin-Related Peptide from a South American Viper ( Bothrops atrox). | J Nat Prod | 2021
Evidence 2 Activity

Activity

50% Cytotoxicity
Toxicity
34.07±6.37 µM
Cytotoxic
50% Cytotoxicity | 34.07±6.37 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Mechanistic Insights into the Leishmanicidal and Bactericidal Activities of Batroxicidin, a Cathelicidin-Related Peptide from a South American Viper ( Bothrops atrox). | J Nat Prod | 2021