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Peptide record

TPDB22200

Antibacterial Hemolysis Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB22200
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from Peptipedia, HemoPI, Hemolytic2, and other sources, with an available 3D structural model.
Sequence
KNWKGIAGMAKKLLGKNWELMEK
Physicochemical Analysis
C122H201N33O30S2
RDCQHFPSTYV
K
2674.26
10.54
6
2
10
+4
4.36
-0.743
76.52
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
11000
411.33
2
Residue Composition
number
2
A
0
R
2
N
0
D
0
C
2
E
0
Q
3
G
0
H
1
I
3
L
6
K
2
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 2 D: 0 C: 0 E: 2 Q: 0 G: 3 H: 0 I: 1 L: 3 K: 6 M: 2 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
23
C122H201N33O30S2
2674.26
10.54
+4
4.36
-0.743
Evidence Records 2 records
Evidence 1 Activity

Activity

6% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
6% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of a novel membrane-destabilizing peptide selectively acting on acidic liposomes. | Biosci Biotechnol Biochem | 2000
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis