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Peptide record

TPDB22197

Antibacterial Hemolysis Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB22197
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from Peptipedia, HemoPI, Hemolytic2, and other sources, with an available 3D structural model.
Sequence
KNWKGIAGMAKKLLGENWELM
Physicochemical Analysis
C110H177N29O28S2
RDCQHFPSTYV
K
2417.91
10.16
4
2
10
+2
2.38
-0.443
83.81
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
11000
454.94
2
Residue Composition
number
2
A
0
R
2
N
0
D
0
C
2
E
0
Q
3
G
0
H
1
I
3
L
4
K
2
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 2 D: 0 C: 0 E: 2 Q: 0 G: 3 H: 0 I: 1 L: 3 K: 4 M: 2 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
21
C110H177N29O28S2
2417.91
10.16
+2
2.38
-0.443
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
5% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of a novel membrane-destabilizing peptide selectively acting on acidic liposomes. | Biosci Biotechnol Biochem | 2000
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis