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Peptide record

TPDB22195

Antibacterial Anticancer Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB22195
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
KLWKKIEKLIKKLLTSIR
Physicochemical Analysis
C107H192N28O23
ANDCQGHMFPYV
K
2238.88
11.19
7
1
8
+6
4.02
-0.283
151.67
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
245.66
2
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
1
E
0
Q
0
G
0
H
3
I
4
L
6
K
0
M
0
F
0
P
1
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 3 L: 4 K: 6 M: 0 F: 0 P: 0 S: 1 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
18
C107H192N28O23
2238.88
11.19
+6
4.02
-0.283
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
236±13 µM
Hemolytic Cytotoxic
50% Hemolysis | 236±13 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Designing Anticancer Peptides by Constructive Machine Learning. | ChemMedChem | 2018
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
50 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: 50% Hemolysis=236±13 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
ChemMedChem. 2018 Jul 6 13(13):1300-1302.