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Peptide record

TPDB22161

Antibacterial Toxicity modified_plain modified
21 amino acids
Basic Information
3D PDB MODEL
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TPDB22161
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 21-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
KLXXKXXFXXKXXFXXKXXKR
Physicochemical Analysis
C60H103N17O10
ANDCEQGHIMPSTWYV
K
1222.59
11.85
6
0
3
+6
2.94
-0.695
18.57
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
5
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 5 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
21
C60H103N17O10
1222.59
11.85
+6
2.94
-0.695
Evidence Records 1 records
Evidence 1 Activity

Activity

63% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
63% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
De novo design of selective antibiotic peptides by incorporation of unnatural amino acids. | J Med Chem | 2007