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Peptide record

TPDB22154

Antibacterial Toxicity modified_plain modified
19 amino acids
Basic Information
3D PDB MODEL
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TPDB22154
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 19-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
KLXXGKXXGFXXGKXKKKK
Physicochemical Analysis
C63H115N19O13
ARNDCEQHIMPSTWYV
K
1346.73
11.29
7
0
2
+7
5.27
-1.153
20.53
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
1
L
7
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 1 K: 7 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
19
C63H115N19O13
1346.73
11.29
+7
5.27
-1.153
Evidence Records 2 records
Evidence 1 Activity

Activity

43.6% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
43.6% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
NOVEL ANTI-MICROBIAL PEPTIDOMIMETIC COMPOUNDS AND METHODS TO CALCULATE ANTI-MICROBIAL ACTIVITY | PATENT US 2012/0197004 A1 | 2012
Evidence 2 Activity

Activity

24.9% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
24.9% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
NOVEL ANTI-MICROBIAL PEPTIDOMIMETIC COMPOUNDS AND METHODS TO CALCULATE ANTI-MICROBIAL ACTIVITY | PATENT US 2012/0197004 A1 | 2012