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Peptide record

TPDB22126

Antibacterial Cell-penetrating Peptides Hemolysis Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB22126
Antibacterial Cell-penetrating Peptides Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
Peptipedia HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Cell-penetrating Peptides, Hemolysis, and other sources) peptide sequence curated from Peptipedia, HemoPI, Hemolytic2, and other sources, with an available 3D structural model.
Sequence
KLLKLLLKLLLKLLK
Physicochemical Analysis
C90H172N20O16
ARNDCEQGHIMFPSTWYV
L
1790.48
11.12
5
0
10
+5
-0.65
1.233
260.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
10
L
5
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 10 K: 5 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
15
C90H172N20O16
1790.48
11.12
+5
-0.65
1.233
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
0.35 µM
Hemolytic Cytotoxic
50% Hemolysis | 0.35 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The amphipathic helix concept: length effects on ideally amphipathic LiKj(i=2j) peptides to acquire optimal hemolytic activity. | Biochim Biophys Acta | 1999
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis