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Peptide record

TPDB22121

Antibacterial Toxicity modified_plain modified
21 amino acids
Basic Information
3D PDB MODEL
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TPDB22121
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 21-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
KLLKKXGKLLKKXGKLLKKAG
Physicochemical Analysis
C99H190N28O20
RNDCEQHIMFPSTWYV
K
2092.77
11.41
9
0
7
+9
5.41
-0.557
116.19
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
6
L
9
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 6 K: 9 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
21
C99H190N28O20
2092.77
11.41
+9
5.41
-0.557
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
1.56 µM
Hemolytic Cytotoxic
<5% Hemolysis | 1.56 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Rational Design of Helix-Stabilized Antimicrobial Peptide Foldamers Containing α,α-Disubstituted Amino Acids or Side-Chain Stapling. | Chempluschem | 2020