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Peptide record

TPDB22107

Antibacterial Antifungal Hemolysis Toxicity standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB22107
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb PD_Hemolysis
standard
No
A 8-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from Peptipedia, CAFPdb, and PD_Hemolysis, with an available 3D structural model.
Sequence
KLFKKLFK
Physicochemical Analysis
C54H90N12O9
ARNDCEQGHIMPSTWYV
K
1051.38
11.00
4
0
4
+4
0.58
-0.300
97.50
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
2
L
4
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 4 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C54H90N12O9
1051.38
11.00
+4
0.58
-0.300
Evidence Records 8 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
<10% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A Comparative Study of the Antimicrobial and Structural Properties of Short Peptides and Lipopeptides Containing a Repetitive Motif KLFK. | Protein Pept Lett | 2019
Evidence 2 Activity

Activity

20% Hemolysis
Toxicity
400 µM
Hemolytic Cytotoxic
20% Hemolysis | 400 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A Comparative Study of the Antimicrobial and Structural Properties of Short Peptides and Lipopeptides Containing a Repetitive Motif KLFK. | Protein Pept Lett | 2019
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
50% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A Comparative Study of the Antimicrobial and Structural Properties of Short Peptides and Lipopeptides Containing a Repetitive Motif KLFK. | Protein Pept Lett | 2019
Evidence 4 Activity

Activity

90% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
90% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A Comparative Study of the Antimicrobial and Structural Properties of Short Peptides and Lipopeptides Containing a Repetitive Motif KLFK. | Protein Pept Lett | 2019
Evidence 5 Activity

Activity

100% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
100% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A Comparative Study of the Antimicrobial and Structural Properties of Short Peptides and Lipopeptides Containing a Repetitive Motif KLFK. | Protein Pept Lett | 2019
Evidence 6 Activity

Activity

100% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
100% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A Comparative Study of the Antimicrobial and Structural Properties of Short Peptides and Lipopeptides Containing a Repetitive Motif KLFK. | Protein Pept Lett | 2019
Evidence 7 Activity

Activity

100% Hemolysis
Toxicity
12.5 µM
Hemolytic Cytotoxic
100% Hemolysis | 12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A Comparative Study of the Antimicrobial and Structural Properties of Short Peptides and Lipopeptides Containing a Repetitive Motif KLFK. | Protein Pept Lett | 2019
Evidence 8 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis