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Peptide record

TPDB22105

Antibacterial Antifungal Hemolysis Toxicity standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB22105
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb PD_Hemolysis
standard
No
A 4-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from Peptipedia, CAFPdb, and PD_Hemolysis, with an available 3D structural model.
Sequence
KLFK
Physicochemical Analysis
C27H46N6O5
ARNDCEQGHIMPSTWYV
K
534.70
10.60
2
0
2
+2
0.29
-0.300
97.50
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
2
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 2 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
4
C27H46N6O5
534.70
10.60
+2
0.29
-0.300
Evidence Records 6 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
400 µM
Hemolytic Cytotoxic
<10% Hemolysis | 400 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A Comparative Study of the Antimicrobial and Structural Properties of Short Peptides and Lipopeptides Containing a Repetitive Motif KLFK. | Protein Pept Lett | 2019
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
400 µM
Hemolytic Cytotoxic
50% Hemolysis | 400 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A Comparative Study of the Antimicrobial and Structural Properties of Short Peptides and Lipopeptides Containing a Repetitive Motif KLFK. | Protein Pept Lett | 2019
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
110 µM
Hemolytic Cytotoxic
50% Hemolysis | 110 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A Comparative Study of the Antimicrobial and Structural Properties of Short Peptides and Lipopeptides Containing a Repetitive Motif KLFK. | Protein Pept Lett | 2019
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
50% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A Comparative Study of the Antimicrobial and Structural Properties of Short Peptides and Lipopeptides Containing a Repetitive Motif KLFK. | Protein Pept Lett | 2019
Evidence 5 Activity

Activity

100% Hemolysis
Toxicity
12.5 µM
Hemolytic Cytotoxic
100% Hemolysis | 12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A Comparative Study of the Antimicrobial and Structural Properties of Short Peptides and Lipopeptides Containing a Repetitive Motif KLFK. | Protein Pept Lett | 2019
Evidence 6 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis