Back to search

Peptide record

TPDB22083

Antibacterial Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB22083
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 24-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
KLKLKLKLKLKLKLKLKLKLKLKL
Physicochemical Analysis
C144H278N36O25
ARNDCEQGHIMFPSTWYV
LK
2914.02
11.55
12
0
12
+12
5.16
-0.050
195.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
12
L
12
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 12 K: 12 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
24
C144H278N36O25
2914.02
11.55
+12
5.16
-0.050
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
<1 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | <1 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Membranolytic Mechanism of Amphiphilic Antimicrobial β-Stranded [KL]n Peptides | Biomedicines | 2022
Evidence 2 Activity

Activity

87% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
87% Hemolysis | 256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Membranolytic Mechanism of Amphiphilic Antimicrobial β-Stranded [KL]n Peptides | Biomedicines | 2022