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Peptide record

TPDB22055

Antibacterial Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB22055
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 37-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
KLFGKVGNLLQKGWQKIKNIGRRIKDFFRNIRPMQEA
Physicochemical Analysis
C202H332N62O48S1
CHSTY
K
4429.30
12.02
10
2
14
+8
7.43
-0.751
84.32
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
124.17
6
Residue Composition
number
1
A
4
R
3
N
1
D
0
C
1
E
3
Q
4
G
0
H
4
I
3
L
6
K
1
M
3
F
1
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 4 N: 3 D: 1 C: 0 E: 1 Q: 3 G: 4 H: 0 I: 4 L: 3 K: 6 M: 1 F: 3 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
37
C202H332N62O48S1
4429.30
12.02
+8
7.43
-0.751
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
12.5 µM
Hemolytic Cytotoxic
0% Hemolysis | 12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial Activity of Cathelicidin-Derived Peptide from the Iberian Mole Talpa occidentalis | Vaccines | 2022
Evidence 2 Activity

Activity

7% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
7% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial Activity of Cathelicidin-Derived Peptide from the Iberian Mole Talpa occidentalis | Vaccines | 2022
Evidence 3 Activity

Activity

16% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
16% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial Activity of Cathelicidin-Derived Peptide from the Iberian Mole Talpa occidentalis | Vaccines | 2022